Monsters, robots, a sinister villain... And a boy who's about to discover that the only way to defeat EVIL is with GENIUS. Thirteen-year-old Alfonso is top of his class at the University of Doom, the super-secret Center of Evil Genius Academia and Mad Science. He longs to be a mad scientist like his father, Dr. Eugenio Frankenstein. But when family nemesis Professor James Moriarty falsely accuses the Frankenstein family of going too far at playing God, they're exiled to an ordinary suburban neighborhood, where they must hide their past to fit in. Despite his father's wishes, Alfonso returns to the University of Doom with his new friend, Sarah Barker, to battle Professor Moriarty and his army of monsters and robots to become the greatest evil genius who ever lived.