Timmy is in Key West, Florida, ostensibly for the honeymoon of his mother and Doorman Dave - if they even got married, which Timmy doubts. Unfortunately for Timmy, crime doesn't take a holiday. And because Total has fled to Cuba, Timmy must rely on a new partner for help: Doorman Dave's nephew Emilio. Meanwhile, a surprise newcomer shows up in Timmy's life and, as if things couldn't get more hectic, Timmy's pants have been stolen by a six-toed cat.

Ineffective detective Timmy Failure's later run is reissued here with a fresh cover look.