The book discusses Explainable (XAI) and Responsive Artificial Intelligence (RAI) for biomedical and healthcare applications. It will discuss the advantages in dealing with big and complex data by using explainable AI concepts in the field of biomedical sciences. The book explains both positive as well as negative findings obtained by explainable AI techniques. It features real time experiences by physicians and medical staff for applied deep learning based solutions. The book will be extremely useful for researchers and practitioners in advancing their studies.